Journal of Food, Agriculture and Environment

Wound healing potential of methanolic extracts of some plants native to Al-Qassim Region, Saudi Arabia

Author(s):

Khaled B. Al-Harbi*, E.A. El-Tigani-Asil, Ahmed F. Ahmed, Ibrahim M. El- Ashmawy, Naser A. Al-Wabel

Recieved Date: 2016-05-15, Accepted Date: 2016-09-12

Abstract:

Folklone phytotherapy is a worldwide practice extensively used for the treatment of various conditions like wounds which are rising as one of the health care obstacles. This study was undertaken to evaluate wound healing effect of methanolic extracts of some plants native to Al-Qassim Region, Saudi Arabia. Wistar rats were used as an animal model for the experiment. Qualitative and quantitative screening of the extracted phytoconstituents were done using standard procedures. A formula of soft paraffin-based ointment (10% conc.) of each crude extract was prepared and used to test wound healing effect in the incision and excision wounded rat models. Wound healing response assessment using inflammation, granulation, regeneration, wound contraction, clossuring rate and reepithelialization parameters were adopted. Phytochemical analysis showed flavonoids, tannins and saponins with various amounts. Healing response signs; viz., inflammation, granulation, regeneration, wound contraction and re-epithelialization were observed in the skin sections of sacrified animals. Extracts of Heliotropium bacciferum, Rhanterium epapposum, Achillea fragrantissima, Artemisia herba alba, Haloxylon salicornicum, Deverra triradiata, Echinops hussoni, Prosopis farcta, Cyperus conglomeratus and Astragalus spinosus were the most potent wound healers that showed complete wound contraction surface (P≤0.05) by the end of the experiment and this may possible due to its high contents of the phytoconstituents.This study concluded that some plant extracts have potential wound healing effect and further investigations are needed to obtain complete profile and its various actions.

Keywords:

Wound healing, methanolic plant extracts, phytoconstituents

---

Journal: Journal of Food, Agriculture and Environment
Year: 2016
Volume: 14
Issue: 3&4
Category: Food and Health
Pages: 18-22

---

Full text for Subscribers

---

Information:

Note to users

The requested document is freely available only to subscribers/registered users with an online subscription to the Journal of Food, Agriculture & Environment. If you have set up a personal subscription to this title please enter your user name and password. All abstracts are available for free.

Article purchasing

If you like to purchase this specific document such as article, review or this journal issue, contact us. Specify the title of the article or review, issue, number, volume and date of the publication. Software and compilation, Science & Technology, all rights reserved. Your use of this website details or service is governed by terms of use. Authors are invited to check from time to time news or information.

---

Purchase this Article:   20 Purchase PDF Order Reprints for 15

---

Share this article :