Journal of Food, Agriculture and Environment

Vol 12, Issue 1,2014
Online ISSN: 1459-0263
Print ISSN: 1459-0255

Structures of alfalfa polysaccharides and their antioxidative activities in mice


Yu-jing Zhu, Chong Wang, Yong Ma, Fang-fang Li, Yong Zhang *

Recieved Date: 2013-10-08, Accepted Date: 2014-01-21


Four kinds of alfalfa-derived polysaccharides, API, APII, APIII and APIV, were extracted using Sephadex A-25 cellulose column chromatography. The most plentiful components, APII and APIII, were screened using Sephadex G-200 column chromatography. Data from HPLC, infrared spectroscopy, and NMR analysis showed that APII contained D-glucopyranosyl, D-fructose and APIII-b contained D-fructose, D-rhamnose, and D-glucopyranosyl this last of which has a role in regulating animal immune systems, improving their ability to resist oxidative damage and tumors. In the present study, high doses of APII-a and APIII-b and medium doses of APIII-b were found to improve SOD and GSH-PX activity and reduce MDA levels in mice (P<0.05). The antioxidative functions of these polysaccharides took place in a dose-dependent manner.


Alfalfa polysaccharides, structure identification, antioxidative effects, mice

Journal: Journal of Food, Agriculture and Environment
Year: 2014
Volume: 12
Issue: 1
Category: Agriculture
Pages: 276-280

Full text for Subscribers

Note to users

The requested document is freely available only to subscribers/registered users with an online subscription to the Journal of Food, Agriculture & Environment. If you have set up a personal subscription to this title please enter your user name and password. All abstracts are available for free.

Article purchasing

If you like to purchase this specific document such as article, review or this journal issue, contact us. Specify the title of the article or review, issue, number, volume and date of the publication. Software and compilation, Science & Technology, all rights reserved. Your use of this website details or service is governed by terms of use. Authors are invited to check from time to time news or information.

Purchase this Article:   20 Purchase PDF Order Reprints for 15

Share this article :