Journal of Food, Agriculture and Environment

Vol 3, Issue 3&4,2005
Online ISSN: 1459-0263
Print ISSN: 1459-0255

Mucuna pruriens (L.) DC – A novel drug for learning and memory retrieval


M. N. Poornachandra 1, Salma Khanam 1, B. G. Shivananda 1, T. N. Shivananda 2*, R. Dris 3

Recieved Date: 2005-04-19, Accepted Date: 2005-08-22


Powdered seeds (drug) of M. pruriens are known to possess many medicinal properties and cure many ailments such as nervous disorders, diarrhea, Parkinson’s disease etc. In the present study the drug has been evaluated for heuristic processes in rats. The drug was administered to Wistar male rats weighing approximately 150–200 grams at one gram per kilogram body weight. The rats were classified into 3 groups to evaluate the impact of drug on learning and memory retrieval processes. Group I received no drug during training (10 days) and memory retrieval (7 days) sessions, Group II received drug during only memory retrieval session and Group III received drug during both training and memory retrieval sessions. The results suggested that the Group I and Group II recorded 65±2.2% learning compared to 90±2.5% of Group III, on 10th day of evaluation showing an improvement of 25% in learning skills. Results on memory retrieval, assessed on 17th day suggested that Group I exhibited 58±8.3% memory retrieval compared to 73±6.1% in Group II. An increase of 15% memory retrieval in Group II over Group I was significant due to administration of drug during memory retrieval session only. Group III exhibited 93±3.3% memory retrieval, which was 35% increase over Group I and 20% increase over Group II that was statistically significant. These results suggest significant effect of drug on learning skills and memory retrieval processes.


M. pruriens, L-dopa, learning, memory retention, memory retrieval

Journal: Journal of Food, Agriculture and Environment
Year: 2005
Volume: 3
Issue: 3&4
Category: Food and Health
Pages: 13-15

Full text for Subscribers

Note to users

The requested document is freely available only to subscribers/registered users with an online subscription to the Journal of Food, Agriculture & Environment. If you have set up a personal subscription to this title please enter your user name and password. All abstracts are available for free.

Article purchasing

If you like to purchase this specific document such as article, review or this journal issue, contact us. Specify the title of the article or review, issue, number, volume and date of the publication. Software and compilation, Science & Technology, all rights reserved. Your use of this website details or service is governed by terms of use. Authors are invited to check from time to time news or information.

Purchase this Article:   20 Purchase PDF Order Reprints for 15

Share this article :